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Clinical trials show that GLP-1RAs demonstrate therapeutic potential for Pso, especially when paired with traditional systemic treatments like acitretin [17,57]

The new US Administrations broader policy goals to rebalance prices between the US and rest of world brought new challenges in the UK: in September 2025, Eli Lilly implemented a UK-wide list price increase of up to 170% for Mounjaro paid for out-out-pocket, where the UK will be a 2bn+ market by the end of 2025

Efficacy and safety of dulaglutide monotherapy compared with glimepiride in East-Asian patients with type 2 diabetes in a multicentre, double-blind, randomized, parallel-arm, active comparator, phase III trial