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This narrative review synthesizes data from randomized controlled trials (RCTs) and real-world evidence (RWE) on Wegovy (semaglutide 2.4 mg, a recombinant DNA-derived GLP-1RA) in obesity with CVD, with a focus on SELECT, mediation analyses suggesting weight-independent CV effects, and outcomes in obesity-related HFpEF

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Certain medications, supplements, and substances can reduce effectiveness or trigger adverse reactionsunderstanding these interactions helps you maximize your weight loss journey safely

Semaglutide is available in both injectable (Ozempic, Wegovy) and oral (Rybelsus) forms.

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