how overweight do you need to be for glp 1 GLP-1 Agonists: Using Semaglutide, Tirzepatide, and Orforglipron Weight Loss and Obesity ๐ญ Thinking about GLP-1 because
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10.1136/bmj.326.7404.1427 [DOI] [PMC free article] [PubMed] [Google Scholar] 58
doi: 10.1007/s12035-023-03342-7
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Drug-drug interactions and metabolic concerns Pharmacokinetic Interactions Anticoagulant and antiplatelet effects: The risk of bleeding increases by approximately 40%-70% among patients taking SSRIs, with the greatest elevations observed when these agents are combined with anticoagulants such as warfarin, antiplatelet agents like aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs)
39 In the SCALE trial, which enrolled 3,731 overweight or obese adults, liraglutide 3.0 mg daily was shown to reduce both systolic and diastolic BP, with average delta of 2.8 mmHg (95% CI [3.56, 2.09) and 0.9 mmHg (95% CI [1.41, 0.37), respectively
Jonathan Cheng, MD, PhD, serves as Medical Director
