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The slowed gastric emptying that contributes to appetite suppression can cause food to sit in the stomach longer than usual

The ATTAIN-MAINTAIN trial validated that patients can switch from tirzepatide to orforglipron and maintain their weight loss, establishing a potential sequential treatment paradigm: injectable first for maximum loss, then oral maintenance

: Developed for type 2 diabetes

Calcif Tissue Int (2015) 97(5):50615.10.1007/s00223-015-0037-y 22 MabilleauGMieczkowskaAChappardD

However, rapid escalation should only be done under medical supervision to avoid side effects like nausea and dizziness

Then Eli Lilly has to go ahead and drop a dang bombshell and interrupt my plans