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A replicate design was applied so that the within-participant variability for the reference product (1G oral semaglutide) could be determined, to enable the application of widened or reference-scaled bioequivalence acceptance criteria for highly variable drugs [28, 29]

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Medically reviewed by Emily Bigby, MD, Physician at Ivm Health Disclaimer: Compounded Medications: Compounded semaglutide and compounded tirzepatide are not FDA-approved

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