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doi: 10.1038/s41573-021-00337-8 52 NahraRWangTGaddeKMOscarssonJStumvollMJermutusLet al
A sustained 14 mmHg reduction in systolic pressure translates to roughly a 40 to 50% reduction in stroke risk and a 20 to 30% reduction in coronary events over the long term
Most patients regain weight quickly
With a 2.4 mg dose of pemvidutide at week 48, a phase 2 obesity trial of pemvidutide (MOMENTUM 48-week trial) found a mean weight loss of 15.6%
But mechanistically, they are not interchangeable with a supplement that may modestly influence some metabolic markers
& Holst, J
