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GLP-1 receptors are very widely distributed, particularly in the brain, says Daniel Drucker, an endocrinologist at the University of Toronto, who has consulted for Novo Nordisk, Eli Lilly and other companies developing weight-loss drugs

doi:10.1210/jcem.85.8.6717 59 YustaBMatthewsDFlockGBUssherJRLavoieBMaweGMet al

Sattar N, Lee MMY, Kristensen SLet al

[6] Berberine Hydrochloride : Berberine does increase GLP-1, but the effect is tiny and not clinically comparable to prescription GLP-1 drugs and some research suggests it may help with weight loss, but human evidence is limited

J Neurochem (2015) 135(2):3018