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Hypothyroidism slows metabolism and makes weight loss harder, but GLP-1 receptor agonists like semaglutide can still be effective when thyroid hormone is optimized

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Part 1/3 of the GLP-1 Support System

Clinical trials, brain mechanisms, and real-world data reveal a complex picture

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Combination Therapy: While low-risk on their own, GLP-1 RAs increase hypoglycemia risk when combined with insulin or sulfonylureas