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Description
Consequently, GLP-1 that is secreted by intestinal L-cells is rapidly degraded by dipeptylpeptidase-4 (DPP-4) in the endothelium of the portal circulation and in the liver, as well as by a soluble circulating moiety of DPP-4

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Further research is warranted to elucidate underlying mechanisms and optimize patient selection.

The clinical results so far are hard to ignore

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