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Description
Efficacy and safety of GLP-1 medicines for type 2 diabetes and obesity

The closest performing GLP-1 medicine in terms of average weight loss is Novo Nordisks CagriSema, an Amylin/GLP-1 dual agonist, which had an average weight loss of 22.7% after 68 weeks in Phase 3 trials

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P., Zachariae C., Skov L., Vilsbll T

Keywords: Obesity, Diabetes, GLP-1 receptor agonist, Depression, Binge-eating disorder, Qualitative Introduction Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of drugs developed initially for treatment of type 2 diabetes (T2D) and then obesity, by mimicking the incretin effect which includes glucose-dependent increased insulin secretion and improved glycaemic control, and inducing weight loss in a dose-dependent manner [1]
