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Food and Drug Administration, Understanding Investigational Drugs , April 2, 2019 GoodRx, Retatrutide for Weight Loss: Availability, Dosage, and More , June 25, 2026 Food and Drug Administration, Expanded Access, accessed June 29, 2026 Eli Lilly, Expanded Access | Compassionate Use | Clinical Trials , accessed June 29, 2026 WBUR | Here & Now, An extraordinary new obesity drug is still awaiting FDA approval

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Its a GLP-1 (glucagon-like peptide-1) receptor agonist that regulates appetite and glucose levels, promoting weight loss as a secondary benefit

Its effects on heart health are still being studied, but research suggests that it might improve heart rate and blood pressure