glp 1 updates 6-months off GLP-1 update : r/GLPGrad Market Overview: GLP-1 Agonists and
Description
Researchers believe GIP activation may counterbalance some GLP-1 gut effects

Biochem Pharmacol 229:116471 Kelly CA, Sipos JA (2024) Approach to the patient with thyroid nodules: considering GLP-1 receptor agonists
Moreover, semaglutides dominance is reinforced in Canada, where rising obesity prevalence and strong prescribing growth led Health Canada to issue multiple shortage advisories in 2024
Evidence-based guidance supports polyethylene glycol (PEG) for constipation

Questions remain concerning the drugs long-term effects on the body, in particular the GI tract

Taken together, we propose that in HF enhanced activation of afferent renal nerves leads to enhanced activation of efferent renal sympathetic nerves response to GLP-1 possibly via central nervous system, thereby suppressing diuresis and natriuresis (Fig
