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That's the thing I keep coming back to

Unlike sulfonylureas, which stimulate insulin secretion independently of blood glucose and can lead to hypoglycemia, GLP-1RAs improve glycemic control in a glucose-dependent manner, thereby minimizing the risk of hypoglycemia

Though GLP-1 drugs have a high price tag, they currently represent only 6.9% of annual claims, according to survey respondents, said Julie Stich, CEBS, Vice President of Content at the International Foundation

Further supporting this mechanism, peripheral GLP-1 infusion improves glucose tolerance in intact animals, but this benefit is lost following the ablation of vagal signaling (Imeryuz et al., 1997

GLP-1s may offer a dual benefit for patients with chronic conditions like diabetes or obesity who are also struggling with a substance use disorder: one medication can treat both conditions at once, Al-Aly said

Patients who are struggling to build meals around a smaller appetite may benefit from nutritional counseling and coaching rather than relying on a generic list of "GLP-1 foods." MTC's nutrition service focuses on personalized eating guidance and health goals