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Description

arSi89[lag-2p::lag-2(IC)] is a single copy insertion on the LGI site generated from pJC106, with a stop codon replacing a fragment from aa311 to aa 403, which results in a protein truncated three amino acids after the transmembrane domain

Individual results vary and a medical provider will determine your specific treatment plan

Scand J Gastroenterol (2013) 48(10):11529.10.3109/00365521.2013.832366 172 LeeSJLeeJLiKKHollandDMaughanHGuttmanDSet alDisruption of the murine Glp2r impairs Paneth cell function and increases susceptibility to small bowel enteritis

Relevant UK guidance includes: NICE Technology Appraisal for semaglutide (Wegovy) in weight management sets out the criteria for use and monitoring in adults with obesity [4] [5] NICE guideline NG28: Type 2 diabetes in adults: management covers the use of incretin-based therapies in type 2 diabetes [6] NICE Technology Appraisal for tirzepatide (Mounjaro) in type 2 diabetes confirms the scope of UK recommendations for tirzepatide [7] [8] Your prescriber can help assess whether your symptoms are expected, manageable, or warrant a change in treatment