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Prolonged energy deficit and weight loss often reduce circulating insulin levels, and similar reductions in insulin have been observed for GLP1 agonist users

We performed a retrospective pharmacovigilance study based on reports from the FAERS database collected between January 2004 and September 2020

GLP-1 agonists are licensed only for type 2 diabetes and obesity, not rheumatoid arthritis or other autoimmune conditions