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Inflammation: Inflammation is regulated by DPP-4 clearance of proteins that modulate immune responses

The study was approved by the Regional Ethical Review Board in Stockholm (registration numbers EPN 2015/57931/2 and 202301601-02)

Zhang, U

Unlike traditional GLP-1 drugs, tirzepatide targets both GLP-1 and GIP receptors, unlocking superior weight-loss results compared to semaglutide (OZEMPIC, WEGOVY)

Both influence the PPAR-gamma transcription factor, which regulates lipid metabolism

The guidance notes that treatment decisions should consider more than weight loss alone, including potential benefits and harms, cost, medication availability, comorbidities, patient preferences, and long-term health goals