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While the list of pathophysiologic defects continues to grow, the ominous octet provides a representation of 8 key defects found in T2DM ( Figure 1 )
Topical administration of a liraglutide-containing ophthalmic solution reversed this pathology, markedly increasing tear fluid secretion and attenuating diabetes-induced inflammation in the lacrimal gland [75]

Hamburger, D
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Stronger cardiovascular data: The SELECT trial provides robust evidence for cardiovascular protection

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Fundam Clin Pharmacol 33(5):567580
