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We also send reminder texts and emails based on the date the patient received their last medication shipment

In the early 1970s, Dupre et al

Source: Heymsfield et al., JAMA, 2021

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For patients whose clinical situation requires moderate rather than maximal weight loss, such as those with early-stage metabolic dysfunction where 10-12% weight loss is sufficient to normalize metabolic parameters, orforglipron's efficacy profile may be adequate and its oral convenience advantageous