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Addiction Weight Loss Drugs May Also Curb Substance Use Disorders GLP-1 drugs affect reward circuits to reduce alcohol, opioid, and nicotine use
Its challenging to study, as looking at the kidney, liver and blood vessels require more invasive procedures, though we may be able to use animal studies to fill the gaps

Anorectic and aversive effects of GLP-1 receptor agonism are mediated by brainstem cholecystokinin neurons, and modulated by GIP receptor activation

JAMA Intern Med 2024

doi: 10.2337/dc11-s231 [DOI] [PMC free article] [PubMed] [Google Scholar] 28
Shift Towards Targeted, Multi-Benefit Medications: GLP-1 receptor agonists not only help regulate blood sugar but also promote weight loss, offering patients additional benefits beyond traditional diabetes medications
