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A 2026 review in the New England Journal of Medicine noted that questions about long-term dosing and durability of results remain open areas of research, not settled strategy

Track your body composition over time, not just your scale weight

Weight loss injections, primarily glucagon-like peptide-1 (GLP-1) receptor agonists such as semaglutide (Wegovy) and tirzepatide (Zepbound), work through multiple mechanisms to promote weight reduction

These include: Pancreatitis : Sudden severe stomach pain, nausea, or vomiting Gallbladder problems : Pain in the upper abdomen, yellowing of skin or eyes Kidney issues : Decreased urination, swelling, or rapid weight gain Low blood sugar (when used with insulin or sulfonylureas): Dizziness, sweating, confusion, shakiness Allergic reactions : Rash, swelling of the face or throat, difficulty breathing Mood or mental health changes : Depression, irritability, or suicidal thoughts Rare eye complications: A very small increased risk of non-arteritic ischemic optic neuropathy (NAION) has been reported Thyroid cancer : Unusual lumps in the neck, hoarseness, or trouble swallowing Its best to speak to your doctor before starting GLP-1-based treatments to understand the potential side effects and risks, especially if you have existing health conditions

Dietitians play a critical role in: Adjusting meal timing and composition Managing fat and fiber intake appropriately Identifying trigger foods Supporting hydration strategies The result