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Genetic differences in appetite signaling pathways, insulin sensitivity, and metabolic rate can explain why some people lose significant weight while others see minimal results

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Available, withdrawn, and investigational GLP-RAs are listed in this paper

Most diabetic patients (61.2%) exhibited poor glycemic control

A new real-world study in JAMA Network Open looked at 126,984 adults with overweight or obesity, without diabetes, who started a GLP-1RA between 2019 and 2024