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Description
Avoid use in patients with a history of suicidal behavior, and discontinue therapy in patients who develop suicidal ideation
10.1038/s41598-021-88612-x 45 KimM.PlattM
Some patients respond better to tirzepatide's dual-pathway action after trying semaglutide alone, or vice versa
Still, januvia interactions matter when combined with agents that cause hypoglycemia, such as insulin or sulfonylureas
Semaglutide works on GLP-1 receptors only, while tirzepatide targets both GLP-1 and GIP receptors
Evidence for acceleration is therefore presented as directional (high, medium, or low) rather than absolute totals
