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People with obesity are more likely to suffer from psychiatric conditions, including anxiety and depression, than people without obesity

Proton-pump inhibitors (PPIs) or H2-receptor antagonists (like famotidine) offer pharmacological support for refractory GERD, and clinical evidence shows they are safe to combine with GLP-1 therapy

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While ketone bodies are physiologic molecules, their high levels reduce the physiological pH of the blood and induce ketoacidosis, leading to increasing metabolic dysfunction