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Cox proportional hazards models were used to evaluate the association between GLP-1 RA use and osteoporosis risk, adjusting for age, sex, BMI, blood pressure, lipid profile, renal function, osteocalcin, vitamin D levels, HbA1c, statin use, antihypertensive medication use, and smoking status

(27) Additionally, GLP-1 agonists were linked to lower hospitalization rates, mortality, and a reduced risk of lower limb amputation (HR: 0.83, 95% CI: 0.671.03)