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Hormonal shifts, metabolic slowdown, and body composition changes make weight loss increasingly difficult with each passing year

The use of prazosin, an 1-adrenergic receptor blocker, showed that the ability of GLP-1RAs to reduce TNF- in plasma was disrupted, signifying the vital role of 1-adrenergic receptors in the anti-inflammatory action of GLP-1RAs

If these strategies don't help within 4 weeks, ask your provider about bloodwork to check iron, B12, and thyroid function

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