glp-1/gip/glucagon triple agonist Retatrutide: The Triple-Agonist Guide to Weight Loss, Appetite Control & Metabolic Reset In the ATTAIN-1 phase 3,
Description
An update on the drug will occur in 2Q 2024

Contemporary classification of Glucagon-like peptide 1 receptor agonists (GLP1RAs)

doi: 10.2337/dci24-0003 [DOI] [PubMed] [Google Scholar] 46

Its like a rubber bandyou pull it hard and it snaps back quickly. For that reason, clinicians typically counsel patients that GLP-1 medications are a long-term treatment, similar to medications for high blood pressure or diabetes

They found other small peptides that control insulin and appetite by acting on two or even three metabolic switches instead of just one

When you combine appetite suppression from GLP-1 activation with the insulin-sensitizing effects of GIP stimulation and the thermogenic boost from glucagon receptor engagement, you get a compounding metabolic effect that no single-receptor or dual-receptor agonist can match
