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Adverse side effects are one of the leading reasons individuals discontinue therapy or are unable to increase their dose, even if they havent yet reached their desired goals

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If trials continue to go well, experts estimate: FDA submission: 2026 Possible approval: late 20262027 Thats best-case, not guaranteed

Consider switching to a non-oral method or adding a barrier method of contraception for 4 weeks after initiation and 4 weeks after each dose escalation

They reabsorb approximately 95% of filtered carnitine under normal conditions