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Instead, it stems from subcortical and autonomic mechanisms that hit adults aged 65 and older and patients with Type 2 diabetes particularly hard, highlighting an urgent need for proactive clinical supervision and medication de-escalation

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Retatrutide could be particularly beneficial for: Individuals struggling with obesity Patients with type 2 diabetes People at risk for cardiovascular disease Those with metabolic syndrome Its triple-receptor strategy makes it a promising candidate for patients dealing with multiple weight- and metabolism-related health issues

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Lancet 389:13991409 Davies MJ, Aronne LJ, Caterson ID et al (2018) Liraglutide and cardiovascular outcomes in adults with overweight or obesity: a post hoc analysis from SCALE randomized controlled trials