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Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trial [published correction appears in Lancet

+ Why theyre leading the way in 2026 GLP-1 medications are receptor agonists that mimic a hormone our bodies make after we eat: glucagon-like peptide-1 (GLP-1)

Tirzepatide is a dual agonist at both GIP and GLP-1 receptors

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Often that means crackers, toast, soup, fruit, or other foods that are easy to eat but protein-poor

And the clinical evidence for cycling between them