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Can I switch from Wegovy to retatrutide

As its full safety profile remains under investigation, the following reflects current available data and known class effects: Gastrointestinal symptoms are the most common: nausea, vomiting, diarrhoea, and constipation, particularly during dose escalation

(2017) The gluco- and liporegulatory and vasodilatory effects of glucose-dependent insulinotropic polypeptide (GIP) are abolished by an antagonist of the human GIP receptor
Diabetes Ther 2023;14:415e24

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Patch-clamp recordings revealed that bath application of GLP-1 or exendin-4 increases the spontaneous firing frequency and decreases the excitation threshold for MC firing in olfactory bulb