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This FDA-approved medication works primarily through appetite suppression and enhanced satiety, leading to reduced caloric intake and subsequent fat mobilization

Given the observed increased risk of colorectal cancer among patients receiving GLP-1 receptor agonists, clinicians should approach long-term prescribing of these agents with careful consideration, particularly in individuals with additional risk factors for colorectal cancer, such as a family history, obesity, inflammatory bowel disease, or long-standing type 2 diabetes

With those caveats stated clearly, here is what practitioners who are using this approach are documenting

If you experience any suspected side effects from any medicine, report them via the MHRA Yellow Card Scheme at yellowcard.mhra.gov.uk or through the Yellow Card app

and Lee et al