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Evidence indicates that AS progresses more rapidly in patients with T2DM, characterized by more unstable plaques that are prone to triggering adverse cardiovascular events such as myocardial infarction and stroke

However, a small sample found that Lira did not significantly change levels of the hepatic fat oxidation marker -hydroxybutyrate, although it reduced liver fat [68]

GLP-1 receptor agonists such as semaglutide (Ozempic and Wegovy), and tirzepatide (Mounjaro and Zepbound) have been most commonly associated with gastrointestinal side effects, such as nausea, vomiting, diarrhea and constipation

It is important to avoid injecting lixisenatide after a meal or in case of a missed meal

Reasons Why Some People Hit a Plateau in Their Weight Loss Journey Several reasons can contribute to hitting a weight loss plateau

For some, the once-weekly injection may be more convenient than daily pills