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5 - PMID 37786396 - Tirzepatide vs Insulin Lispro Added to Basal Insulin in Type 2 Diabetes: The SURPASS-6 Randomized Clinical Trial, JAMA (2023)

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Preclinical studies suggest they may reduce substance cravings and consumption by modulating dopamine signaling, though human evidence remains preliminary and requires further clinical trials

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By comparison, prescription GLP-1 drugs increase hormone levels by hundreds of thousands of percent and remain active far longer in the body

Semaglutide (Ozempic) has become a household name in weight loss, but medical guidelines and emerging research show that certain people face real safety risks with this medication