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DPP-4 inhibitors are also acceptable for use in diabetes patients because GLP-1 is rapidly deactivated by DPP-4

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Weight Loss In SUSTAIN 1 and PIONEER 1 trials, with patients managing early-stage diabetes with diet and exercise alone, subcutaneous semaglutide 1.0 mg led to a mean weight reduction of 4.5 kg, whereas oral semaglutide 14 mg achieved a 3.7 kg reduction [28]

Therefore, a systematic review of the current literature on the management of postoperative GLP-1 analogue usage after metabolic surgery was performed