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Adv Sci 12(4)
Data availability The atomic coordinates and the electron microscopy maps have been deposited in the Protein Data Bank (PDB) under accession number 7D68 and Electron Microscopy Data Bank (EMDB) under accession number EMD-30590, respectively

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158162 Recently, abstinent users would experience reduced appetite and increased metabolic rates during this period

GLP-1 agonist drugs like semaglutide (brand: Ozempic, Rybelsus) and tirzepatide (brand: Mounjaro) have been making waves in western markets, particularly the United States, over the past year as weight loss drugs, with major impacts expected for the food industry due to their appetite-suppressing capabilities
These peptides demonstrated total DPP-IV resistance and enhanced in vitro insulin secretion
