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Notably, the Canagliflozin and Renal Events in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) trial, the first dedicated kidney outcome trial evaluating canagliflozin in people with type 2 diabetes mellitus and CKD, demonstrated a substantial reduction in the risk of kidney events [46]

doi: 10.1016/s0167-0115(02)00157-x

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This could increase demand within Medicare Advantage plans operating in the state and place new emphasis on care coordination, prior authorization workflows, and provider education