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The rapid rise in prescriptions for GLP-1 receptor agonists medications such as semaglutide (Wegovy, Ozempic) used for type 2 diabetes and obesity is creating a challenge for oncological fluorodeoxyglucose positron emission tomographycomputed tomography (FDG PET-CT) imaging

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Introduction Incretin hormones, glucagon-like peptide-1 (GLP-1), and glucose-dependent insulinotropic polypeptide (GIP) lower the postprandial glucose as they potentiate glucose-stimulated insulin release from the pancreatic beta cells (1),(2)
42 Likewise, a systematic review of 41 studies involving overweight or obese participants showed a significant reduction in total-hip BMD (0.0100.015 g/cm 2 ) after weight-loss interventions lasting six months or longer, whereas lumbar-spine BMD remained stable

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