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[DOI] [PubMed] [Google Scholar] 43.Lpez-Mora DA, et al

The substantial weight loss achieved with GLP-1 receptor agonists and dual GIP/GLP-1 agonistsapproximately 15% with semaglutide 2.4 mg (Wegovy) and up to 21% with higher doses of tirzepatide (Zepbound) in clinical trialsoccurs primarily through appetite suppression and reduced caloric intake rather than increased metabolic rate

Obes Sci Pract

Butler PC, Elashoff M, Elashoff R, et al

Cirincione B, LaCreta F, Sager P, Mager DE

In a meta-analysis with patients with T1D, weight loss with liraglutide 1.8 mg was estimated at ~5 kg compared to placebo (62), and there was a dose-response effect