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Patients who travel frequently: Injectable GLP-1 medications require cold-chain storage, sharps containers, and the logistics of traveling with needles and vials

Ali notes that fatigue may also result from anemia or other nutritional deficiencies caused by Mounjaro-induced appetite loss, which may prevent adequate intake of protein, healthy fats, or whole grains

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Research Sources: New England Journal of Medicine: Tirzepatide as Compared with Semaglutide for the Treatment of Obesity. May 11, 2025

While individual results vary, many users report initial benefits -such as reduced appetite, improved digestion, and fewer cravings-within the first few days to 2 weeks

At the same time, studies have also shown a correlation between low B12 levels and obesity so taking vitamin B12 supplements to maintain healthy B12 levels can promote weight loss