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0.81] was observed after 6 months

Moreno, C., Mistry, M

The only approved oral GLP-1 formulation Novo Nordisks Rybelsus (semaglutide) combines the same peptide as Novos injectable Ozempic and Wegovy formulations with an absorption enhancer (sodium N -(8-[2-hydroxybenzoyl] amino) caprylate, or SNAC)

While GLP-1 (7-36amide) and GLP-1 (737) are equally potent to stimulate the secretion of insulin and c-peptide [181], GLP-1 (137) has a much lower insulinotropic efficacy [[80], [81], [82]]

One of those side effects is called gastroparesis

Rapid dose escalation significantly increases the severity and duration of gastrointestinal side effects