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For assessing the change in peripheral markers of inflammation, a linear model was constructed for each protein using the protein value (pg/mg) as dependent variable and the treatment group (veh-PBS, veh-LPS, and sema-LPS) and time (2h, 24h, or 5d after the last LPS injection) as independent variables with interaction effects

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Acute infusion of exendin 939 significantly increased mean basal glucose levels and glucose area-under-the-curve, and markedly lowered the insulin:glucose ratios (Calabria et al., 2012)