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Busui, J

Bottom Line GLP-1 agonists have a place in medicine as treatment for Type 2 diabetes and obesity, offering benefits in blood sugar control and weight loss

The receptor-focused density map of Ex4-D-Ala conf
GLP-1 receptor agonists reduce appetite and improve metabolic function to promote gradual, sustainable weight loss

Single molecules with GLP-1 and Gcg co-agonism were created to take advantage of the beneficial effects of both GLP-1 and Gcg on energy metabolism while limiting Gcg induction of hyperglycemia (Day et al., 2009)

Collectively, these data suggest that FFAs increase intracellular Ca 2+ by stimulating the influx of Ca 2+ via the cell-surface (most likely L-type) Ca 2+ channels [292]
