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Abstract Objective: Having demonstrated short-term weight loss with liraglutide in this group of obese adults, we now evaluate safety/tolerability (primary outcome) and long-term efficacy for sustaining weight loss (secondary outcome) over 2 years

Clinical and experimental studies demonstrate that GLP-1RAs decrease hepatic fat content and fibrosis markers, reduce circulating pro-inflammatory cytokines, and promote favorable adipokine profiles, collectively dampening immune activation [9,25]
[DOI] [PubMed] [Google Scholar] 42.Nexoe-Larsen CC, Sorensen PH, Hausner H, Agersnap M, Baekdal M, Bronden A, et al

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