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Eur J Pharmacol (2011) 660(1):1318

MEASUREMENTS OF KIDNEY DISEASE DEVELOPMENT AND PROGRESSION The diagnosis and assessment of CKD involves a combination of measurements to assess the extent of underlying kidney damage and function, as well as monitoring the progression of disease

76,322,323,324 Therefore, mitochondrial targeting of NAMPT activity may be used to avoid the toxicity observed in first-generation inhibitors and provide an enhanced therapeutic window

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