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A 2025 study reported evidence of telomere length stabilization or modest lengthening, raising the possibility that metabolic therapies may influence pathways related to genomic stability and replicative lifespan [16]

This can be diagnosed in people with fatty liver who are either overweight/obese or have type 2 diabetes, or have normal weight with at least two metabolic risk factors, as shown in Figure 1

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SGLT2i have a Class of Recommendation 2a in HF with mildly reduced ejection fraction (HFmrEF)