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Semaglutide is a selective glucagon-like peptide-1 (GLP-1) receptor agonist
Semaglutide is not recommended during pregnancy due to limited safety data and animal study findings
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Multivariate analysis showed no difference between placebo and liraglutide arms in HbA1c at 6 months (HbA1c:0.2mmol/mol, 11.3, 11.6, p=0.98) however, at 12 months HbA1c was significantly higher in the liraglutide arm (HbA1c:10.9mmol/mol, 1.1, 20.6, p=0.032)
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