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higher doses require split injections) 12 weeks: 1236 syringes 24 weeks: 2472 syringes Bacteriostatic Water (10 mL bottles): Use ~1.0 mL per vial for reconstitution

Very limited Phase 3 trial sites exist in major Australian cities

Lyophilized (unmixed) powder is significantly more stable: suitable for refrigerator storage within a 3-6 month window, or frozen at -20C or below for longer durations

The landscape differs substantially between the FDA-approved Mounjaro and the investigational Retatrutide

For patients significantly above A1C target on Metformin alone, adding Retatrutide offers potential to reach goal without stacking multiple additional oral medications