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Think long-term: View your GLP-1 medication as an aid, not the main component

However, it is essential to note that when additional pharmacological intervention is required to control diabetes mellitus, the choice between SGLT-2 inhibitors and GLP-1 RAs should be based on the patients individual needs and the specific medications already being used

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The convenience of a once-weekly shot also means it generally fits easily into patients lives

Prices for semaglutide and tirzepatide drugs are higher in the U.S

As for mortality, both SGLT-2 inhibitors and GLP-1RA are similar in reducing both total and CV deaths, but SGLT-2 inhibitors only are superior to DPP-4 inhibitors for both deaths, whereas GLP-1RA are superior to DPP-4 inhibitors for total death, but equal for CV death