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doi: 10.1016/j.jalz.2013.12.005

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In rats, the drugs, known as glucagon-like-peptide-1 (GLP-1) receptor agonists, have been shown to cause thyroid C-cell tumors

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Clinical trials may involve different patient populations, doses, treatment lengths, diabetes status, lifestyle support, and study designs

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doi:10.1111/j.1463-1326.2010.01259.x 141

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With these points in mind, we undertook a broad assessment of published clinical data, curating the body weight loss (% from baseline), glycosylated hemoglobin levels (HbA1c), and nausea responses (% patients reporting) from the SUSTAIN 3, SUSTAIN 7, SCALE Diabetes, SURPASS 2, and STEP 2 trials (64, 66, 67) ( Figures 1AC )

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