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Do not use if the liquid appears cloudy, discolored, or contains particles

Measure the total volume in the vial (if possible, by drawing it all out with a syringe, noting the volume, and injecting it back)

Map which body areas are affected

Increasing pericardial pressure leads to a compensatory increase in diastolic pressure in all chambers until they become similar to the pericardial pressure

faecium) Ampicillin (if susceptible) 2 g IV q4h 812 weeks (limited success, ~50%) Rare: Ampicillin + Streptomycin (if streptomycin susceptible) 5 Multidrug-resistant (penicillin, vancomycin & aminoglycoside resistant) Daptomycin 1012 mg/kg IV q24h + Ampicillin 2 g IV q4h or Ceftaroline 600 mg IV q8h Last resort: Linezolid 600 mg IV/PO q12h 8 weeks (bacteriostatic, high relapse risk) Therapeutic Drug Monitoring Gentamicin (q812h dosing): Peak 34 g/mL
